Cancer is life-threatening. We know that cancer cells proliferate by accumulating many mutations in multiple cellular pathways. They invade and metastasize by defying normal constraints. But cancer cells have their inherent weakness. They gave up many of the cellular controls and safeguards for the sake of proliferation. Through intensive research, we have identified several genes essential to the proliferation of cancer cells. By interfering with these gene targets in both cell culture and animal models, we have been able to identify anticancer compounds capable of causing massive cancer cell death without harming normal cells. We are conducting further pre-clinical studies on these promising novel anticancer agents. We may be on the verge of seeing the light at the end of the tunnel in the prolonged war against cancer, a curse to human life and health.